Tottenham Hotspur are predicted to secure a victory against Brentford. Historical head-to-head data significantly favors Tottenham, with a strong record of wins against Brentford. The match odds reflect this, with Tottenham being the favorites. The Asian Handicap of -0.25 suggests a slight advantage for Tottenham, and based on the historical data, they have the upper hand. The injury reports indicate both teams are missing key players, but this is unlikely to drastically shift the predicted outcome, given the overall dominance shown by Tottenham. The current form and historical performance of Tottenham against Brentford are the deciding factors here, which is the main basis for this prediction. The over/under market set at 2.5 goals anticipates a game with several goals. Considering Tottenham's attacking prowess and their previous matches against Brentford, it is very likely this match will be high-scoring.