This Premier League match between Brentford and Tottenham Hotspur presents an intriguing matchup based on historical data and current odds. Examining the head-to-head record reveals a strong advantage for Tottenham, consistently prevailing against Brentford. The recent encounters suggest a pattern favoring Tottenham's attacking prowess, with several high-scoring games. The injury data suggests both teams are dealing with absentees, but the impact of these injuries requires careful consideration. Analyzing the match odds, Tottenham are favored slightly, but the Asian Handicap offers a potentially profitable angle. Considering the Asian Handicap of -0.25 in favor of Tottenham, the odds suggest a close game. The head-to-head results heavily favour Tottenham, indicating their ability to find the net against Brentford's defence. The injury situations of both teams could impact the game, but I expect Tottenham to cope better. The over/under market has set the line at 2.5 goals, reflecting the likelihood of a higher-scoring game given the historical context and the attacking styles of both teams. My prediction leans towards Tottenham to win the match. Their head-to-head advantage, coupled with slightly favorable odds, makes them the more likely victor. The historical data points to goals, and thus I am predicting Over 2.5 goals. Based on the analysis, I predict Tottenham to win, covering the Asian Handicap of -0.25. Therefore, I predict that Tottenham will win the match. This assessment incorporates both historical data and current betting odds to formulate a comprehensive prediction.