The stage is set for an intriguing Premier League clash between Crystal Palace and Fulham. Examining the data, several factors point towards a home victory for Crystal Palace. Their head-to-head record against Fulham is quite compelling, with Palace holding a clear advantage in recent encounters. Analyzing the past ten matches, Crystal Palace has demonstrated a stronger ability to secure wins, particularly when playing at home. Looking at the injury reports, both teams are carrying significant injury concerns. The number of key players sidelined for both sides might impact their overall performance. Crystal Palace’s home advantage could be crucial. The Asian Handicap favors Crystal Palace slightly, reflecting their perceived edge. Given the historical data and home advantage, betting on Crystal Palace to win with a -0.25 handicap seems a reasonable choice. The match odds also support this, with a lower price for a home win. Considering the recent form and defensive capabilities of both teams, an Under 2.5 goals prediction appears sensible. While Premier League matches can be unpredictable, the potential for a low-scoring game seems probable based on the provided data. In conclusion, all things considered, Crystal Palace appears to have the upper hand. Therefore, I predict a home win for Crystal Palace, with Under 2.5 goals scored in the match.