This Championship clash sees Southampton hosting Millwall. The match data indicates Southampton as the clear favorite, reflected in the odds. Their home win odds are significantly lower than Millwall's away win, and the Asian Handicap favors Southampton, suggesting a predicted victory by at least a goal. Injuries could play a factor, with Millwall notably impacted by absences, potentially weakening their defensive structure. Southampton's injury list, while present, appears less debilitating. This disparity in squad availability likely contributes to Southampton's favored status. Analyzing set-piece potential is crucial. Southampton's attacking prowess, combined with a potential defensive vulnerability in Millwall due to injury, could translate into opportunities from free kicks and corners. Considering the -0.75 Asian Handicap, Southampton needs to win by at least two goals to cover the spread. The Over/Under line is set at 2.75 goals, suggesting a high-scoring game is anticipated. Given Southampton’s attacking strength and Millwall’s likely weakened defense, the over seems like a good bet. Further, the win draw loss market supports the home team to win, with a significant difference between the odds. Given the data and the current context, I predict a Southampton win, potentially with multiple goals, covering the Asian Handicap. The over goals bet also presents a strong probability. The injury data further reinforces the probability of a Southampton win, and the Asian Handicap also supports a strong home team showing, suggesting Southampton will attack from the beginning to control the game.