AS Roma currently occupies a position in the upper reaches of the league, positioning them as strong contenders for Champions League qualification, and they will be eager to secure a victory in this match. Their home record is excellent, with a string of recent wins. A significant boost comes in attack, with top scorer Dovbyk returning from injury. However, the squad faces notable absences: Spinazzola is suspended, and the availability of midfield core Pellegrini is uncertain. Furthermore, some players have been called up for the Africa Cup of Nations, placing considerable strain on midfield rotations and wing defence. Genoa currently languishes in the relegation zone, facing a dire situation in their fight to avoid demotion. Their recent form has been unstable, and their away defence has been riddled with vulnerabilities. Compounding their problems, the squad is in crisis: first-choice goalkeeper Leali is suspended, and the substitute goalkeeper, Sigurist, is injured, potentially leading to the third-choice goalkeeper making his season debut; key defender De Winter is suspended due to a red card, and the absence of Onana and other attackers means that seven crucial players are unavailable. This significantly weakens their overall attacking and defensive capabilities. AS Roma has a dominant head-to-head record against Genoa in their last ten encounters, with seven wins, two draws, and only one loss. Their home performance has been particularly strong, creating a clear advantage. This historical record underpins the fundamental disparity in strength for this match. AS Roma currently possesses one of the most solid defences in Serie A, conceding only ten goals in sixteen league matches. In contrast, Genoa's defence has performed poorly, conceding twenty-four goals, placing them near the bottom of the league. They also face a severe shortage of personnel in the goalkeeper and central defender positions. Against AS Roma's attacking system orchestrated by Dybala, with Lukaku or Dovbyk leading the line, Genoa's makeshift defence is expected to struggle. Although AS Roma holds an overall advantage, they also have concerns. Spinazzola's suspension and the absence of Lorenzo Pellegrini could diminish their wing penetration and midfield control. It is anticipated that Genoa will adopt a highly conservative tactical approach away from home, focusing on deep defence and time-wasting to restrict AS Roma's attacking space. Consequently, AS Roma may face a difficult challenge in breaking down the opposition, with the match potentially turning into a stalemate. Considering the fundamental factors and data trends, the current level of support is somewhat insufficient, failing to fully reflect AS Roma's overall advantage. In this context, Genoa is expected to hold their ground and remain undefeated away from home. Score Prediction: 1-1, 2-2