AS Roma takes on Genoa in a Serie A clash, with Roma looking to solidify their position. Given their superior league standing and recent form, Roma are the clear favorites, with a strong home record. Genoa, currently in the lower half of the table, will have a tough challenge. Roma's recent home form, as indicated by their win against Como, alongside the head-to-head records favoring Roma, points towards a likely victory for the home side. The odds reflect this, suggesting Roma should overcome Genoa. The Asian Handicap of -0.75 in favor of AS Roma indicates the expectation that they will win by more than a goal. Considering the scoring trends in their recent matches and the Over/Under line set at 2.25, a game with multiple goals is anticipated. Genoa, while capable of causing upsets, has struggled against stronger teams on the road. The injuries on both sides, while present, don't significantly tilt the balance. Roma's goal difference, despite a few losses, suggests they possess a decent attacking ability which will likely be key in this match against Genoa’s weaker defense. Considering the match overview, the status being 'STATE_NOT_STARTED', further details cannot be provided about how the match will unfold, the prediction is primarily based on the data provided including the ranking, recent form, head-to-head records and match odds. In conclusion, with Roma's superior league standing, home advantage, and the betting odds favoring them, a win for AS Roma seems the most probable outcome, with the match likely to see over 2 goals. The forecast is to expect a dominant display from Roma, with Genoa finding it difficult to gain a result.