AS Roma faces Genoa in an Italian Serie A match. Historical data shows Roma with a strong head-to-head record, suggesting a home advantage. Considering the injury data, both teams have key players sidelined. Looking at the odds, the Asian Handicap is set at -0.75 in favor of AS Roma, with home odds at 0.83 and away odds at 1.03. This suggests a strong expectation of a Roma win. The match odds also favor Roma significantly. Over/Under is set at 2.25 goals, with over odds at 1.10. Given Roma's offensive capabilities and Genoa's potential to score, over 2.25 goals looks probable. Furthermore, the analyst's recent and all-time statistics, although showing a negative profit rate, indicate a reasonable win rate, providing additional context. I predict AS Roma to win the match, covering the Asian Handicap, and the total goals will be over 2.25.