The Serie A match between Pisa and Juventus presents a compelling David versus Goliath narrative. With Juventus heavily favored, the odds suggest a comfortable victory for the away side, but football is rarely predictable, and the absence of key players on both sides adds an element of uncertainty. Juventus, boasting significantly stronger odds for a win, clearly holds the upper hand. Their offensive capabilities and defensive solidity are expected to pose a significant challenge for Pisa. However, the absence of several key players due to injury could impact their overall performance. The absence of these key figures might force Juventus to adapt their strategy, potentially allowing Pisa to exploit any vulnerabilities that arise. Pisa, despite being the clear underdog, cannot be entirely dismissed. They will be playing at home and, with a well-organized defensive approach and tactical astuteness, could potentially frustrate Juventus. A disciplined display, coupled with some luck, might even allow them to secure a draw, although the probability is relatively low. Their hopes rest on exploiting any weaknesses Juventus may display and capitalizing on any scoring opportunities that come their way. Considering the current match data, including injury information, the Asian Handicap favors Juventus, implying the expectation of a multi-goal victory. However, with several key injuries affecting both teams, an Under 2.5 goals prediction appears more prudent. While Juventus is likely to win, Pisa's defensive setup and the potential for a less fluid Juventus attack suggest that the final score might not be a high-scoring affair. In conclusion, the prediction leans towards a Juventus win, but the match is not without potential for surprises. The Under 2.5 goals market appears safer. While a dominant Juventus performance is expected, the absence of key players on both sides and Pisa's home advantage introduces elements of unpredictability, making this Serie A clash one to watch closely.