This match pits Eintracht Braunschweig against league leaders Schalke 04. Schalke's superior league position and form, holding a significant points advantage, clearly indicates their dominance. While Braunschweig has struggled, Schalke has consistently performed, suggesting a likely away win. Analyzing the provided data, Schalke’s away win odds are relatively attractive at 2.20, indicating a reasonable probability of success. The Asian Handicap of +0.25 in favor of Schalke suggests that even a draw benefits our prediction. The over/under market, with a line of 2.25 goals, presents an interesting opportunity. Considering Schalke's strong defensive record (only 8 goals conceded in 16 matches) and Braunschweig's goal-scoring struggles (18 goals in 16 matches), an under bet appears prudent. While both teams have injury concerns, Schalke’s squad depth and superior form should allow them to overcome these absences and secure a win. Taking everything into consideration, the prediction leans towards a Schalke victory, potentially with a low-scoring game. Schalke should have enough quality to win the match even with the absence of key players.